This is a good time to mention that Clojure has ClojureScript, which is the full language hosted on JavaScript, and compiled using Google Closure (sigh about the naming confusion) advanced compilation mode, with dead code elimination and full-program optimization.
[context: I used to write in CL and used Parenscript before I switched to Clojure]
There is also babashka(https://github.com/borkdude/babashka) which is basically a subset of Clojure suitable for scripting (including Clojure concurrency features) running on GraalVM
[context: I used to write in CL and used Parenscript before I switched to Clojure]